Here's our Windows XP Tip for.. April 1, 2003
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More on Corrupt Boot Sectors
If you suddenly get a corrupt partition boot sector error after you've been running a hard disk for an extended period of time, you may wonder how it happens. One cause (one we recently encountered) is a defective disk controller. However, hardware isn't necessarily the problem. There is a chance that some software can corrupt the partition boot sector.

So how do you identify the problem? You can try to eliminate one factor at a time. It could be the hard disk; try another one. It could be the controller; try another controller if possible.